Comparison of Primary Virus Isolation in Pulmonary Alveolar Macrophages and Four Different Continuous Cell Lines for Type 1 and Type 2 Porcine Reproductive and Respiratory Syndrome Virus

Comparison of Primary Virus Isolation in Pulmonary Alveolar Macrophages and Four Different Continuous Cell Lines for Type 1 and Type 2 Porcine Reproductive and Respiratory Syndrome Virus

Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) has a highly restricted cellular tropism. In vivo, the virus primarily infects tissue-specific macrophages in the nose, lungs, tonsils, and pharyngeal lymphoid tissues. In vitro however, the MARC-145 cell line is one of the few PRRSV suscep...

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Bibliographic Details
Main Authors: Jiexiong Xie, Nick Vereecke, Sebastiaan Theuns, Dayoung Oh, Nathalie Vanderheijden, Ivan Trus, Jannes Sauer, Philip Vyt, Caroline Bonckaert, Christian Lalonde, Chantale Provost, Carl A. Gagnon, Hans Nauwynck
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Vaccines
Subjects:
PRRSV
virus isolation/production
macrophages
MARC-145
PK15<sup>Sn-CD163</sup>
PK15<sup>S10-CD163</sup>
Online Access:https://www.mdpi.com/2076-393X/9/6/594

Internet

https://www.mdpi.com/2076-393X/9/6/594

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