Chromatin 3D structure reconstruction with consideration of adjacency relationship among genomic loci

Chromatin 3D structure reconstruction with consideration of adjacency relationship among genomic loci

Abstract Background Chromatin 3D conformation plays important roles in regulating gene or protein functions. High-throughout chromosome conformation capture (3C)-based technologies, such as Hi-C, have been exploited to acquire the contact frequencies among genomic loci at genome-scale. Various compu...

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Bibliographic Details
Main Authors: Fang-Zhen Li, Zhi-E Liu, Xiu-Yuan Li, Li-Mei Bu, Hong-Xia Bu, Hui Liu, Cai-Ming Zhang
Format: Article
Language:English
Published: BMC 2020-07-01
Series:BMC Bioinformatics
Subjects:
3D organization
Chromosome
Hi-C
Reconstruction
MDS
Online Access:http://link.springer.com/article/10.1186/s12859-020-03612-4

Internet

http://link.springer.com/article/10.1186/s12859-020-03612-4

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