Chromatin 3D structure reconstruction with consideration of adjacency relationship among genomic loci
Abstract Background Chromatin 3D conformation plays important roles in regulating gene or protein functions. High-throughout chromosome conformation capture (3C)-based technologies, such as Hi-C, have been exploited to acquire the contact frequencies among genomic loci at genome-scale. Various compu...
Main Authors: | Fang-Zhen Li, Zhi-E Liu, Xiu-Yuan Li, Li-Mei Bu, Hong-Xia Bu, Hui Liu, Cai-Ming Zhang |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-07-01
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Series: | BMC Bioinformatics |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12859-020-03612-4 |
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