Molecular Epidemiology of EGFR Mutations in Asian Patients with Advanced Non-Small-Cell Lung Cancer of Adenocarcinoma Histology - Mainland China Subset Analysis of the PIONEER study.

Epidermal growth factor receptor (EGFR) mutations are the strongest response predictors to EGFR tyrosine kinase inhibitors (TKI) therapy, but knowledge of the EGFR mutation frequency on lung adenocarcinoma is still limited to retrospective studies. The PIONEER study (NCT01185314) is a prospective mo...

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Main Authors: Yuankai Shi, Junling Li, Shucai Zhang, Mengzhao Wang, Shujun Yang, Ning Li, Gang Wu, Wei Liu, Guoqing Liao, Kaican Cai, Liang'an Chen, Meizhen Zheng, Ping Yu, Xiuwen Wang, Yunpeng Liu, Qisen Guo, Ligong Nie, Jiwei Liu, Xiaohong Han
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4657882?pdf=render