Runs of homozygosity in spontaneous abortions from families with recurrent pregnancy loss

Runs of homozygosity in spontaneous abortions from families with recurrent pregnancy loss

Recurrent pregnancy loss (RPL) is a severe reproductive pathology with a significant component of unexplained etiology. Extended homozygous regions as a possible etiological factor for RPL were sought in the genomes of embryos. Twenty-two paired first-trimester spontaneously aborted embryos from ele...

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Bibliographic Details
Main Authors: N. A. Skryabin, S. A. Vasilyev, T. V. Nikitina, D. I. Zhigalina, R. R. Savchenko, N. P. Babushkina, M. E. Lopatkina, A. A. Kashevarova, I. N. Lebedev
Format: Article
Language:English
Published: Institute of Cytology and Genetics of Siberian Branch of the Russian Academy of Sciences 2019-03-01
Series:Vavilovskij Žurnal Genetiki i Selekcii
Subjects:
recurrent pregnancy loss
array-based comparative genomic hybridization
runs of homozygosity
spontaneous abortions
genomic imprinting
Online Access:https://vavilov.elpub.ru/jour/article/view/1943

Internet

https://vavilov.elpub.ru/jour/article/view/1943

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