A protocol to automatically calculate homo-oligomeric protein structures through the integration of evolutionary constraints and NMR ambiguous contacts

Protein assemblies are involved in many important biological processes. Solid-state NMR (SSNMR) spectroscopy is a technique suitable for the structural characterization of samples with high molecular weight and thus can be applied to such assemblies. A significant bottleneck in terms of both effort...

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Bibliographic Details
Main Authors: Davide Sala, Linda Cerofolini, Marco Fragai, Andrea Giachetti, Claudio Luchinat, Antonio Rosato
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
NMR
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037019303423