The Role of Pseudomonas aeruginosa ExoY in an Acute Mouse Lung Infection Model

The Role of Pseudomonas aeruginosa ExoY in an Acute Mouse Lung Infection Model

The effector protein Exotoxin Y (ExoY) produced by Pseudomonas aeruginosa is injected via the type III secretion system (T3SS) into host cells. ExoY acts as nucleotidyl cyclase promoting the intracellular accumulation of cyclic nucleotides. To what extent nucleotidyl cyclase activity contributes to...

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Bibliographic Details
Main Authors: Christina Kloth, Bastian Schirmer, Antje Munder, Tane Stelzer, Justin Rothschuh, Roland Seifert
Format: Article
Language:English
Published: MDPI AG 2018-05-01
Series:Toxins
Subjects:
Pseudomonas aeruginosa
bacterial effector protein
nucleotidyl cyclase
lung infection
T3SS
Online Access:http://www.mdpi.com/2072-6651/10/5/185

Internet

http://www.mdpi.com/2072-6651/10/5/185

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