An essential role of RNF187 in Notch1 mediated metastasis of hepatocellular carcinoma

An essential role of RNF187 in Notch1 mediated metastasis of hepatocellular carcinoma

Abstract Background Aberrant activation of Notch signaling has been causally linked to the metastasis of hepatocellular carcinoma (HCC), however the underlying molecular mechanisms are still poorly understood. RING finger protein 187 (RNF187) was recently revealed to be a driver of several cancers,...

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Bibliographic Details
Main Authors: Lei Zhang, Jiewei Chen, Juanjuan Yong, Liang Qiao, Leibo Xu, Chao Liu
Format: Article
Language:English
Published: BMC 2019-09-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Hepatocellular carcinoma
RNF187
Notch signaling
Metastasis
Online Access:http://link.springer.com/article/10.1186/s13046-019-1382-x

Internet

http://link.springer.com/article/10.1186/s13046-019-1382-x

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