CTLA-4 Mediates Inhibitory Function of Mesenchymal Stem/Stromal Cells

CTLA-4 Mediates Inhibitory Function of Mesenchymal Stem/Stromal Cells

Mesenchymal stem/stromal cells (MSCs) are stem cells of the connective tissue, possess a plastic phenotype, and are able to differentiate into various tissues. Besides their role in tissue regeneration, MSCs perform additional functions as a modulator or inhibitor of immune responses. Due to their p...

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Bibliographic Details
Main Authors: Timo Gaber, Kerstin Schönbeck, Holger Hoff, Cam Loan Tran, Cindy Strehl, Annemarie Lang, Sarah Ohrndorf, Moritz Pfeiffenberger, Eric Röhner, Georg Matziolis, Gerd-R. Burmester, Frank Buttgereit, Paula Hoff
Format: Article
Language:English
Published: MDPI AG 2018-08-01
Series:International Journal of Molecular Sciences
Subjects:
mesenchymal stem/stromal cells
immune modulation
CTLA-4
hypoxia
fracture healing
regeneration
Online Access:http://www.mdpi.com/1422-0067/19/8/2312

Internet

http://www.mdpi.com/1422-0067/19/8/2312

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