Chymase Dependent Pathway of Angiotensin II Generation and Rapeseed Derived Peptides for Antihypertensive Treatment of Spontaneously Hypertensive Rats

Chymase Dependent Pathway of Angiotensin II Generation and Rapeseed Derived Peptides for Antihypertensive Treatment of Spontaneously Hypertensive Rats

The contribution of chymase, one of the enzymes responsible for angiotensin II generation in non-ACE pathway, remains unclear in the development of hypertension. The aim of the study was to investigate chymase inhibition as potential antihypertensive therapy in spontaneously hypertensive rats (SHR)....

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Bibliographic Details
Main Authors: Iwona Baranowska, Olga Gawrys, Malwina M. Roszkowska-Chojecka, Bozena Badzynska, Dagmara Tymecka, Krzysztof H. Olszynski, Elzbieta Kompanowska-Jezierska
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Pharmacology
Subjects:
chymase
CPPs
rapakinin
RAAS
chymostatin
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.658805/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.658805/full

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