P14<sup>ARF</sup>: The Absence that Makes the Difference

P14<sup>ARF</sup> is a tumor suppressor encoded by the CDKN2a locus that is frequently inactivated in human tumors. P14<sup>ARF</sup> protein quenches oncogene stimuli by inhibiting cell cycle progression and inducing apoptosis. P14<sup>ARF</sup> functions can be...

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Bibliographic Details
Main Authors: Danilo Cilluffo, Viviana Barra, Aldo Di Leonardo
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/11/7/824