Effective inhibition of HCMV UL49 gene expression and viral replication by oligonucleotide external guide sequences and RNase P

<p>Abstract</p> <p>Background</p> <p>Human cytomegalovirus (HCMV) is a ubiquitous herpesvirus that typically causes asymptomatic infections in healthy individuals but may lead to serious complications in newborns and immunodeficient individuals. The emergence of drug-re...

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Bibliographic Details
Main Authors: Zhang Xin, Li ShiQian, Zeng ZhiFeng, Li YueQin, Li HongJian, Zhang WenJun, Zou Yi, Zhou TianHong
Format: Article
Language:English
Published: BMC 2010-05-01
Series:Virology Journal
Online Access:http://www.virologyj.com/content/7/1/100