Increased mucosal IL-12 expression is associated with relapse of ulcerative colitis

Increased mucosal IL-12 expression is associated with relapse of ulcerative colitis

Abstract Background The role of IL-12/23 in the pathogenesis of ulcerative colitis (UC) is unclear. We analyzed mucosal IL-12/23 expression and its relationship with endoscopic severity, histological activity, and UC relapse. Methods Rectal biopsies were collected from 70 UC patients with clinical r...

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Bibliographic Details
Main Authors: Kazuhiko Uchiyama, Tomohisa Takagi, Katsura Mizushima, Mariko Kajiwara-Kubota, Saori Kashiwagi, Yuki Toyokawa, Makoto Tanaka, Yuma Hotta, Kazuhiro Kamada, Takeshi Ishikawa, Hideyuki Konishi, Mitsuo Kishimoto, Yuji Naito, Yoshito Itoh
Format: Article
Language:English
Published: BMC 2021-03-01
Series:BMC Gastroenterology
Subjects:
IL-12
IL-23
Ulcerative colitis
Rectal mucosa
Relapse
Online Access:https://doi.org/10.1186/s12876-021-01709-5

Internet

https://doi.org/10.1186/s12876-021-01709-5

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