Epidermal Growth Factor (EGF) Augments the Invasive Potential of Human Glioblastoma Multiforme Cells via the Activation of Collaborative EGFR/ROS-Dependent Signaling

Epidermal Growth Factor (EGF) Augments the Invasive Potential of Human Glioblastoma Multiforme Cells via the Activation of Collaborative EGFR/ROS-Dependent Signaling

Abnormal secretion of epidermal growth factor (EGF) by non-neuronal cells (e.g., glioma-associated microglia) establishes a feedback loop between glioblastoma multiforme (GBM) invasion and a functional disruption of brain tissue. Considering the postulated significance of this vicious circle for GBM...

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Bibliographic Details
Main Authors: Maciej Pudełek, Kamila Król, Jessica Catapano, Tomasz Wróbel, Jarosław Czyż, Damian Ryszawy
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:International Journal of Molecular Sciences
Subjects:
Glioblastoma multiforme
epidermal growth factor
invasion
EGFR
ROS
Online Access:https://www.mdpi.com/1422-0067/21/10/3605

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https://www.mdpi.com/1422-0067/21/10/3605

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