Single-Cell TCR Sequencing Reveals the Dynamics of T Cell Repertoire Profiling During Pneumocystis Infection

Single-Cell TCR Sequencing Reveals the Dynamics of T Cell Repertoire Profiling During Pneumocystis Infection

T cell responses play critical roles in host adaptive immunity against Pneumocystis. However, the dynamics and diversity of the T cell immune repertoire in human immunodeficiency virus (HIV)-negative Pneumocystis pneumonia (PCP) remains unclear. In this study, single-cell RNA and single-cell T cell...

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Bibliographic Details
Main Authors: Hu-Qin Yang, Yi-Shan Wang, Kan Zhai, Zhao-Hui Tong
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Microbiology
Subjects:
Pneumocystis pneumonia
T cell receptors
single-cell TCR sequencing
single-cell RNA sequencing
T cell immune repertoire
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2021.637500/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2021.637500/full

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