Leishmania infantum arginase: biochemical characterization and inhibition by naturally occurring phenolic substances

Leishmania infantum arginase: biochemical characterization and inhibition by naturally occurring phenolic substances

Inhibition of Leishmania arginase leads to a decrease in parasite growth and infectivity and thus represents an attractive therapeutic strategy. We evaluated the inhibitory potential of selected naturally occurring phenolic substances on Leishmania infantum arginase (ARGLi) and investigated their an...

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Bibliographic Details
Main Authors: Andreza R. Garcia, Danielle M. P. Oliveira, Ana Claudia F. Amaral, Jéssica B. Jesus, Ana Carolina Rennó Sodero, Alessandra M. T. Souza, Claudiu T. Supuran, Alane B. Vermelho, Igor A. Rodrigues, Anderson S. Pinheiro
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Journal of Enzyme Inhibition and Medicinal Chemistry
Subjects:
leishmania infantum
visceral leishmaniasis
arginase
inhibitor
rosmarinic acid
caffeic acid
Online Access:http://dx.doi.org/10.1080/14756366.2019.1616182

Internet

http://dx.doi.org/10.1080/14756366.2019.1616182

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