Automated and Accurate Estimation of Gene Family Abundance from Shotgun Metagenomes.

Shotgun metagenomic DNA sequencing is a widely applicable tool for characterizing the functions that are encoded by microbial communities. Several bioinformatic tools can be used to functionally annotate metagenomes, allowing researchers to draw inferences about the functional potential of the commu...

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Bibliographic Details
Main Authors: Stephen Nayfach, Patrick H Bradley, Stacia K Wyman, Timothy J Laurent, Alex Williams, Jonathan A Eisen, Katherine S Pollard, Thomas J Sharpton
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-11-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1004573