Gut Microbiota and Bacterial DNA Suppress Autoimmunity by Stimulating Regulatory B Cells in a Murine Model of Lupus
Autoimmune diseases, such as systemic lupus erythematosus, are characterized by excessive inflammation in response to self-antigens. Loss of appropriate immunoregulatory mechanisms contribute to disease exacerbation. We previously showed the suppressive effect of vancomycin treatment during the “act...
Main Authors: | Qinghui Mu, Michael R. Edwards, Brianna K. Swartwout, Xavier Cabana Puig, Jiangdi Mao, Jing Zhu, Joe Grieco, Thomas E. Cecere, Meeta Prakash, Christopher M. Reilly, Christopher Puglisi, Prathyusha Bachali, Amrie C. Grammer, Peter E. Lipsky, Xin M. Luo |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2020-11-01
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Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fimmu.2020.593353/full |
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