Oral Bioavailability Enhancement of Raloxifene with Nanostructured Lipid Carriers

Raloxifene hydrochloride (RLX) shows poor bioavailability (<2%), high inter-patient variability and extensive gut metabolism (>90%). The objective of this study was to develop nanostructured lipid carriers (NLCs) for RLX to enhance its bioavailability. The NLC formulations were produced with g...

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Bibliographic Details
Main Authors: Aditya Murthy, Punna Rao Ravi, Himanshu Kathuria, Shrinivas Malekar
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Nanomaterials
Subjects:
Online Access:https://www.mdpi.com/2079-4991/10/6/1085