Chromatin topology is coupled to Polycomb group protein subnuclear organization

Chromatin topology is coupled to Polycomb group protein subnuclear organization

Polycomb Group (PcG) proteins regulate gene expression and genome architecture. Using super-resolution microscopy and molecular simulations, Waniet al. describe the organization of PcG proteins into hundreds of nano-scale protein clusters and suggest these clusters shape genome architecture.

Bibliographic Details
Main Authors: Ajazul H. Wani, Alistair N. Boettiger, Patrick Schorderet, Ayla Ergun, Christine Münger, Ruslan I. Sadreyev, Xiaowei Zhuang, Robert E. Kingston, Nicole J. Francis
Format: Article
Language:English
Published: Nature Publishing Group 2016-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms10291

Internet

https://doi.org/10.1038/ncomms10291

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