Hepatocyte TMEM16A Deletion Retards NAFLD Progression by Ameliorating Hepatic Glucose Metabolic Disorder

Hepatocyte TMEM16A Deletion Retards NAFLD Progression by Ameliorating Hepatic Glucose Metabolic Disorder

Abstract Nonalcoholic fatty liver disease (NAFLD) is the most prevalent form of chronic liver disease, and the mechanisms underpinning its pathogenesis have not been completely established. Transmembrane member 16A (TMEM16A), a component of the Ca2+‐activated chloride channel (CaCC), has recently be...

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Bibliographic Details
Main Authors: Jia‐Wei Guo, Xiu Liu, Ting‐Ting Zhang, Xiao‐Chun Lin, Yu Hong, Jie Yu, Qin‐Yan Wu, Fei‐Ran Zhang, Qian‐Qian Wu, Jin‐Yan Shang, Xiao‐Fei Lv, Jing‐Song Ou, Jia‐Guo Zhou, Rui‐Ping Pang, Bao‐Dong Tang, Si‐Jia Liang
Format: Article
Language:English
Published: Wiley 2020-05-01
Series:Advanced Science
Subjects:
glucose metabolic disorder
GLUT2
hepatic steatosis
nonalcoholic fatty liver disease
TMEM16A
VAMP3
Online Access:https://doi.org/10.1002/advs.201903657

Internet

https://doi.org/10.1002/advs.201903657

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