The human melanoma side population displays molecular and functional characteristics of enriched chemoresistance and tumorigenesis.

The human melanoma side population displays molecular and functional characteristics of enriched chemoresistance and tumorigenesis.

Melanoma remains the most lethal skin cancer, mainly because of high resistance to therapy. Side population (SP) cells are found in many types of cancer and are usually enriched in therapy-resistant as well as tumorigenic cells. Here, we identified a Hoechst dye-effluxing SP in a large series of hum...

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Bibliographic Details
Main Authors: Jasper Wouters, Marguerite Stas, Lies Gremeaux, Olivier Govaere, Anke Van den Broeck, Hannelore Maes, Patrizia Agostinis, Tania Roskams, Joost J van den Oord, Hugo Vankelecom
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3789681?pdf=render

Internet

http://europepmc.org/articles/PMC3789681?pdf=render

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