Associations of LEP, CRH, ICAM-1, and LINE-1 methylation, measured in saliva, with waist circumference, body mass index, and percent body fat in mid-childhood

Associations of LEP, CRH, ICAM-1, and LINE-1 methylation, measured in saliva, with waist circumference, body mass index, and percent body fat in mid-childhood

Abstract Background Genetics explains a small proportion of variance in body mass index at the population level. Epigenetics, commonly measured by gene methylation, holds promise for understanding obesity risk factors and mechanisms. Methods Participants were 431 adolescents aged 10–15 years. BMI z-...

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Bibliographic Details
Main Authors: Jocelyn Dunstan, Joseph P. Bressler, Timothy H. Moran, Jonathan S. Pollak, Annemarie G. Hirsch, Lisa Bailey-Davis, Thomas A. Glass, Brian S. Schwartz
Format: Article
Language:English
Published: BMC 2017-03-01
Series:Clinical Epigenetics
Subjects:
Obesity
Epigenetics
DNA methylation
Sex differences
LEP
CRH
Online Access:http://link.springer.com/article/10.1186/s13148-017-0327-5

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http://link.springer.com/article/10.1186/s13148-017-0327-5

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