Synsepalum dulcificum extracts exhibit cytotoxic activity on human colorectal cancer cells and upregulate c-fos and c-jun early apoptotic gene expression

Synsepalum dulcificum extracts exhibit cytotoxic activity on human colorectal cancer cells and upregulate c-fos and c-jun early apoptotic gene expression

Objective: To explore cytotoxicity of Synsepalum dulcificum (S. dulcificum) Daniell (Sapotaceae) on human colon cancer (HCT-116 and HT-29), human monocytic leukemia (THP-1) and normal (HDFn) cell lines, and its effect on the expression of early apoptotic genes, c-fos and c-jun. Methods: Leaf, stem a...

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Bibliographic Details
Main Authors: Jichang Seong, Glenn G Oyong, Esperanza C Cabrera
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2018-01-01
Series:Asian Pacific Journal of Tropical Biomedicine
Subjects:
synsepalum dulcificum
colon cancer
monocytic leukemia
apoptosis
c-fos
c-jun
Online Access:http://www.apjtb.org/article.asp?issn=2221-1691;year=2018;volume=8;issue=3;spage=173;epage=178;aulast=Seong

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http://www.apjtb.org/article.asp?issn=2221-1691;year=2018;volume=8;issue=3;spage=173;epage=178;aulast=Seong

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