Changes Related to Age in Natural and Acquired Systemic Self-IgG Responses in Malaria

Background. Absence of acquired protective immunity in endemic areas children leads to higher susceptibility to severe malaria. To investigate the involvement of regulatory process related to self-reactivity, we evaluated potent changes in auto-antibody reactivity profiles in children and older subj...

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Bibliographic Details
Main Authors: Romuald Dassé, Didier Lefranc, Sylvain Dubucquoi, Patricia Dussart, Virginie Dutoit-Lefevre, Boualem Sendid, François Sombo Mambo, Patrick Vermersch, Lionel Prin
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:Interdisciplinary Perspectives on Infectious Diseases
Online Access:http://dx.doi.org/10.1155/2011/462767