Central administration of C-X-C chemokine receptor type 4 antagonist alleviates the development and maintenance of peripheral neuropathic pain in mice.

<h4>Aim</h4>To explore the roles of C-X-C chemokine receptor type 4 (CXCR4) in spinal processing of neuropathic pain at the central nervous system (CNS).<h4>Methods</h4>Peripheral neuropathic pain (PNP) induced by partial sciatic nerve ligation (pSNL) model was assessed in mi...

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Bibliographic Details
Main Authors: Xin Luo, Wai Lydia Tai, Liting Sun, Qiu Qiu, Zhengyuan Xia, Sookja Kim Chung, Chi Wai Cheung
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/25119456/?tool=EBI