An Integrated Systems Biology Approach Identifies TRIM25 as a Key Determinant of Breast Cancer Metastasis

An Integrated Systems Biology Approach Identifies TRIM25 as a Key Determinant of Breast Cancer Metastasis

At the root of most fatal malignancies are aberrantly activated transcriptional networks that drive metastatic dissemination. Although individual metastasis-associated genes have been described, the complex regulatory networks presiding over the initiation and maintenance of metastatic tumors are st...

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Bibliographic Details
Main Authors: Logan A. Walsh, Mariano J. Alvarez, Erich Y. Sabio, Marsha Reyngold, Vladimir Makarov, Suranjit Mukherjee, Ken-Wing Lee, Alexis Desrichard, Şevin Turcan, Martin G. Dalin, Vinagolu K. Rajasekhar, Shuibing Chen, Linda T. Vahdat, Andrea Califano, Timothy A. Chan
Format: Article
Language:English
Published: Elsevier 2017-08-01
Series:Cell Reports
Subjects:
ARACNe
MARINa
VIPER
breast
cancer
metastasis
transcription
TRIM25
EFP
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717310318

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http://www.sciencedirect.com/science/article/pii/S2211124717310318

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