PP2A negatively regulates the hypertrophic response by dephosphorylating HDAC2 S394 in the heart

PP2A negatively regulates the hypertrophic response by dephosphorylating HDAC2 S394 in the heart

Cardiovascular disease: A brake for heart muscle growth A regulatory mechanism that controls how cardiac muscle responds to stress could inform development of new therapies for preventing heart failure. Physiological stimuli ranging from heavy exercise to heart attack can induce hypertrophy, an incr...

Full description

Bibliographic Details
Main Authors: Somy Yoon, Taewon Kook, Hyun-Ki Min, Duk-Hwa Kwon, Young Kuk Cho, Mira Kim, Sera Shin, Hosouk Joung, Seung Hoon Jeong, Sumin Lee, Gaeun Kang, Yunchul Park, Yong Sook Kim, Youngkeun Ahn, Julie R. McMullen, Ulrich Gergs, Joachim Neumann, Kyung Keun Kim, Jungchul Kim, Kwang-Il Nam, Young-Kook Kim, Hyun Kook, Gwang Hyeon Eom
Format: Article
Language:English
Published: Nature Publishing Group 2018-07-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-018-0121-2

Internet

https://doi.org/10.1038/s12276-018-0121-2

Similar Items