Role of chitosan on controlling the characteristics and antifungal activity of bioadhesive fluconazole vaginal tablets

Role of chitosan on controlling the characteristics and antifungal activity of bioadhesive fluconazole vaginal tablets

Vaginal fluconazole (FLZ) prolonged release tablets containing chitosan in physical blends with other bioadhesive polymers were designed. Chitosan was mixed with hydroxypropyl methylcellulose (HPMC), guar gum or sodium carboxymethyl cellulose (NaCMC) at different ratios and directly compressed into...

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Bibliographic Details
Main Authors: Rawan A. Fitaihi, Fadilah S. Aleanizy, Samar Elsamaligy, Hanaa A. Mahmoud, Mohsen A. Bayomi
Format: Article
Language:English
Published: Elsevier 2018-02-01
Series:Saudi Pharmaceutical Journal
Subjects:
Fluconazole
Chitosan
Bioadhesive polymers
Prolonged release
Swelling
Antifungal activity
Online Access:http://www.sciencedirect.com/science/article/pii/S1319016417302244

Internet

http://www.sciencedirect.com/science/article/pii/S1319016417302244

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