Effects of Two-by-Two Combination Therapy with Valproic Acid, Lithium Chloride, and Celecoxib on the Angiogenesis of the Chicken Chorioallantoic Membrane

Background: The synergistic effects of valproic acid (VPA), lithium (Li), and celecoxib (CX) have been shown in combination therapy against the proliferation and metastasis of numerous cancers. Angiogenesis plays a critical role in the pathogenesis of tumor growth and metastasis. The aim of the pres...

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Bibliographic Details
Main Authors: Ehsan Afzal, Sedigheh Alinezhad, Marjan Khorsand, Mohammad Javad Khoshnood, Mohammad Ali Takhshid
Format: Article
Language:English
Published: Shiraz University of Medical Sciences 2018-09-01
Series:Iranian Journal of Medical Sciences
Subjects:
Online Access:http://ijms.sums.ac.ir/index.php/IJMS/article/view/3780