Amino acid substitutions of MagA in Klebsiella pneumoniae affect the biosynthesis of the capsular polysaccharide.

Mucoviscosity-associated gene A (magA) of Klebsiella pneumoniae contributes to K1 capsular polysaccharide (CPS) biosynthesis. Based on sequence homology and gene alignment, the magA gene has been predicted to encode a Wzy-type CPS polymerase. Sequence alignment with the Wzy_C and RfaL protein famili...

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Bibliographic Details
Main Authors: Tzu-Lung Lin, Feng-Ling Yang, An-Suei Yang, Hung-Pin Peng, Tsung-Lin Li, Ming-Daw Tsai, Shih-Hsiung Wu, Jin-Town Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3485256?pdf=render