CXC chemokine receptor 7 (CXCR7) regulates CXCR4 protein expression and capillary tuft development in mouse kidney.

BACKGROUND: The CXCL12/CXCR4 axis is involved in kidney development by regulating formation of the glomerular tuft. Recently, a second CXCL12 receptor was identified and designated CXCR7. Although it is established that CXCR7 regulates heart and brain development in conjunction with CXCL12 and CXCR4...

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Bibliographic Details
Main Authors: Sammy Haege, Claudia Einer, Stefanie Thiele, Wiebke Mueller, Sandor Nietzsche, Amelie Lupp, Fabienne Mackay, Stefan Schulz, Ralf Stumm
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3412803?pdf=render