Intracellular mechanisms regulating apoB-containing lipoprotein assembly and secretion in primary hamster hepatocytes

We studied the biogenesis of apolipoprotein B (apoB) in primary hepatocytes isolated from hamster liver, an animal model with striking resemblance to humans in lipoprotein metabolism. Hamster hepatocytes were found to assemble and secrete apoB-containing lipoproteins at a density of VLDL. Intracellu...

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Bibliographic Details
Main Authors: Changiz Taghibiglou, Debbie Rudy, Stephen C. Van Iderstine, Andrea Aiton, Dora Cavallo, Raphael Cheung, Khosrow Adeli
Format: Article
Language:English
Published: Elsevier 2000-04-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S002222752032397X