TLR4-NLRP3-GSDMD-Mediated Pyroptosis Plays an Important Role in Aggravated Liver Injury of CD38-/- Sepsis Mice

Clinically, severe bacterial infection can cause septicemia and multiple organ dysfunction syndrome, especially liver injury. CD38 is closely related to many inflammatory pathways, but its role in liver injury caused by bacterial infection remains unclear. The purpose of this study is to discuss the...

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Bibliographic Details
Main Authors: Huiqing Zhang, Yuna Du, Yujie Guo, Zeyu Wang, Hua Li, Zhe Lv, Lifeng Zeng, Yiguo Chen, Zhengyu Xie, Rong Li
Format: Article
Language:English
Published: Hindawi Limited 2021-01-01
Series:Journal of Immunology Research
Online Access:http://dx.doi.org/10.1155/2021/6687555