Major Effect of Oxidative Stress on the Male, but Not Female, SP-A1 Type II Cell miRNome

Major Effect of Oxidative Stress on the Male, but Not Female, SP-A1 Type II Cell miRNome

Pulmonary surfactant protein A (SP-A) plays an important role in surfactant metabolism and lung innate immunity. In humans there are two proteins, SP-A1 and SP-A2, encoded by SFTPA1 and SFTPA2, respectively, which are produced by the alveolar type II cells (T2C). We sought to investigate the differe...

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Bibliographic Details
Main Authors: George T. Noutsios, Nithyananda Thorenoor, Xuesheng Zhang, David S. Phelps, Todd M. Umstead, Faryal Durrani, Joanna Floros
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Immunology
Subjects:
alveolar epithelium
surfactant protein A
ozone
sex differences
MAPK
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01514/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.01514/full

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