Characterisation of SARS-CoV-2 Lentiviral Pseudotypes and Correlation between Pseudotype-Based Neutralisation Assays and Live Virus-Based Micro Neutralisation Assays

Characterisation of SARS-CoV-2 Lentiviral Pseudotypes and Correlation between Pseudotype-Based Neutralisation Assays and Live Virus-Based Micro Neutralisation Assays

The recent outbreak of a novel Coronavirus (SARS-CoV-2) and its rapid spread across the continents has generated an urgent need for assays to detect the neutralising activity of human sera or human monoclonal antibodies against SARS-CoV-2 spike protein and to evaluate the serological immunity in hum...

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Bibliographic Details
Main Authors: Inesa Hyseni, Eleonora Molesti, Linda Benincasa, Pietro Piu, Elisa Casa, Nigel J Temperton, Alessandro Manenti, Emanuele Montomoli
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Viruses
Subjects:
SARS-CoV-2
wild type virus
lentiviral pseudotypes
biosafety
microneutralisation
serological assays
Online Access:https://www.mdpi.com/1999-4915/12/9/1011

Internet

https://www.mdpi.com/1999-4915/12/9/1011

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