Watching synchronous mitochondrial respiration in the retina and its instability in a mouse model of macular degeneration

Abstract Mitochondrial function declines with age and in some diseases, but we have been unable to analyze this in vivo. Here, we optically examine retinal mitochondrial function as well as choroidal oxygenation and hemodynamics in aging C57 and complement factor H (CFH−/−) mice, proposed models of...

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Bibliographic Details
Main Authors: Pardis Kaynezhad, Ilias Tachtsidis, Asmaa Aboelnour, Sobha Sivaprasad, Glen Jeffery
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-82811-2