How useful are monogenic rodent models for the study of human non-alcoholic fatty liver disease?

Improving understanding of the genetic basis of human non-alcoholic fatty liver disease (NAFLD) has the potential to facilitate risk stratification of affected patients, permit personalised treatment, and inform development of new therapeutic strategies. Animal models have been widely used to interr...

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Bibliographic Details
Main Authors: Jake Peter Mann, Robert Kenneth Semple, Matthew J Armstrong
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-11-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fendo.2016.00145/full