Structural insights into DNA repair by RNase T--an exonuclease processing 3' end of structured DNA in repair pathways.

DNA repair mechanisms are essential for preservation of genome integrity. However, it is not clear how DNA are selected and processed at broken ends by exonucleases during repair pathways. Here we show that the DnaQ-like exonuclease RNase T is critical for Escherichia coli resistance to various DNA-...

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Bibliographic Details
Main Authors: Yu-Yuan Hsiao, Woei-Horng Fang, Chia-Chia Lee, Yi-Ping Chen, Hanna S Yuan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-03-01
Series:PLoS Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24594808/?tool=EBI