A network of heterochronic genes including Imp1 regulates temporal changes in stem cell properties

A network of heterochronic genes including Imp1 regulates temporal changes in stem cell properties

Stem cell properties change over time to match the changing growth and regeneration demands of tissues. We showed previously that adult forebrain stem cell function declines during aging because of increased expression of let-7 microRNAs, evolutionarily conserved heterochronic genes that reduce HMGA...

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Bibliographic Details
Main Authors: Jinsuke Nishino, Sunjung Kim, Yuan Zhu, Hao Zhu, Sean J Morrison
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2013-11-01
Series:eLife
Subjects:
neural stem cell
heterochronic gene
cortical development
Online Access:https://elifesciences.org/articles/00924

Internet

https://elifesciences.org/articles/00924

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