Knocking Out Non-muscle Myosin II in Retinal Ganglion Cells Promotes Long-Distance Optic Nerve Regeneration

Knocking Out Non-muscle Myosin II in Retinal Ganglion Cells Promotes Long-Distance Optic Nerve Regeneration

Summary: In addition to altered gene expression, pathological cytoskeletal dynamics in the axon are another key intrinsic barrier for axon regeneration in the central nervous system (CNS). Here, we show that knocking out myosin IIA and IIB (myosin IIA/B) in retinal ganglion cells alone, either befor...

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Bibliographic Details
Main Authors: Xue-Wei Wang, Shu-Guang Yang, Chi Zhang, Ming-Wen Hu, Jiang Qian, Jin-Jin Ma, Yingchi Zhang, Bin-Bin Yang, Yi-Lan Weng, Guo-Li Ming, Anish R. Kosanam, Saijilafu, Feng-Quan Zhou
Format: Article
Language:English
Published: Elsevier 2020-04-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S221112472030437X

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http://www.sciencedirect.com/science/article/pii/S221112472030437X

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