THE ESSENTIAL BIOLOGY OF THE ENDOPLASMIC RETICULUM STRESS RESPONSE FOR STRUCTURAL AND COMPUTATIONAL BIOLOGISTS

The endoplasmic reticulum (ER) stress response is a cytoprotective mechanism that maintains homeostasis of the ER by upregulating the capacity of the ER in accordance with cellular demands. If the ER stress response cannot function correctly, because of reasons such as aging, genetic mutation or env...

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Bibliographic Details
Main Authors: Sadao Wakabayashi, Hiderou Yoshida
Format: Article
Language:English
Published: Elsevier 2013-03-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037014601197