CD44 plays a functional role in Helicobacter pylori-induced epithelial cell proliferation.

CD44 plays a functional role in Helicobacter pylori-induced epithelial cell proliferation.

The cytotoxin-associated gene (Cag) pathogenicity island is a strain-specific constituent of Helicobacter pylori (H. pylori) that augments cancer risk. CagA translocates into the cytoplasm where it stimulates cell signaling through the interaction with tyrosine kinase c-Met receptor, leading cellula...

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Main Authors: Nina Bertaux-Skeirik, Rui Feng, Michael A Schumacher, Jing Li, Maxime M Mahe, Amy C Engevik, Jose E Javier, Richard M Peek, Karen Ottemann, Veronique Orian-Rousseau, Gregory P Boivin, Michael A Helmrath, Yana Zavros
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-02-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1004663

Internet

https://doi.org/10.1371/journal.ppat.1004663

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