Priming mycobacterial ESX-secreted protein B to form a channel-like structure

Priming mycobacterial ESX-secreted protein B to form a channel-like structure

ESX-1 is a major virulence factor of Mycobacterium tuberculosis, a secretion machinery directly involved in the survival of the microorganism from the immune system defence. It disrupts the phagosome membrane of the host cell through a contact-dependent mechanism. Recently, the structure of the inne...

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Bibliographic Details
Main Authors: Abril Gijsbers, Vanesa Vinciauskaite, Axel Siroy, Ye Gao, Giancarlo Tria, Anjusha Mathew, Nuria Sánchez-Puig, Carmen López-Iglesias, Peter J. Peters, Raimond B.G. Ravelli
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Current Research in Structural Biology
Subjects:
Cryo-EM
EspB
ESX-1
Mycobacteria
Preferential orientation
Online Access:http://www.sciencedirect.com/science/article/pii/S2665928X21000118

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http://www.sciencedirect.com/science/article/pii/S2665928X21000118

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