Depletion of Bone Marrow-Derived Fibrocytes Attenuates TAA-Induced Liver Fibrosis in Mice

Depletion of Bone Marrow-Derived Fibrocytes Attenuates TAA-Induced Liver Fibrosis in Mice

Bone marrow-derived fibrocytes (FC) represent a unique cell type, sharing features of both mesenchymal and hematopoietic cells. FC were shown to specifically infiltrate the injured liver and participate in fibrogenesis. Moreover, FC exert a variety of paracrine functions, thus possibly influencing t...

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Bibliographic Details
Main Authors: Felix Hempel, Martin Roderfeld, Rajkumar Savai, Akylbek Sydykov, Karuna Irungbam, Ralph Schermuly, Robert Voswinckel, Kernt Köhler, Yury Churin, Ladislau Kiss, Jens Bier, Jörn Pons-Kühnemann, Elke Roeb
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Cells
Subjects:
fibrocytes
liver fibrosis
bone marrow
myofibroblasts
thioacetamide (taa)
hsv-tk
Online Access:https://www.mdpi.com/2073-4409/8/10/1210

Internet

https://www.mdpi.com/2073-4409/8/10/1210

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