Cardioprotective Effect of Novel Matrix Metalloproteinase Inhibitors

Cardioprotective Effect of Novel Matrix Metalloproteinase Inhibitors

Background: We recently developed novel matrix metalloproteinase-2 (MMP-2) inhibitor small molecules for cardioprotection against ischemia/reperfusion injury and validated their efficacy in ischemia/reperfusion injury in cardiac myocytes. The aim of the present study was to test our lead compounds f...

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Bibliographic Details
Main Authors: Kamilla Gömöri, Tamara Szabados, Éva Kenyeres, Judit Pipis, Imre Földesi, Andrea Siska, György Dormán, Péter Ferdinandy, Anikó Görbe, Péter Bencsik
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:International Journal of Molecular Sciences
Subjects:
matrix metalloproteinase inhibitor
thiazole and imidazole carboxylic acid derivatives
MMP-2
acute myocardial infarction
cardioprotection
cardiovascular comorbidity
Online Access:https://www.mdpi.com/1422-0067/21/19/6990

Internet

https://www.mdpi.com/1422-0067/21/19/6990

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