VAC chemotherapy with valproic acid for refractory/relapsing small cell lung cancer: a phase II study

VAC chemotherapy with valproic acid for refractory/relapsing small cell lung cancer: a phase II study

Salvage chemotherapy (CT) for relapsing or refractory small cell lung cancer (SCLC) remains disappointing. In vitro experiments showed that valproic acid increases apoptosis of SCLC cell lines exposed to doxorubicin, vindesine and bis(2-chloroethyl)amine. The primary objective of this phase II study...

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Bibliographic Details
Main Authors: Thierry Berghmans, Jean-Jacques Lafitte, Arnaud Scherpereel, Lieveke Ameye, Marianne Paesmans, Anne-Pascale Meert, Benoit Colinet, Christian Tulippe, Luc Willems, Nathalie Leclercq, Jean-Paul Sculier, for the European Lung Cancer Working Party
Format: Article
Language:English
Published: European Respiratory Society 2015-10-01
Series:ERJ Open Research
Online Access:http://openres.ersjournals.com/content/1/2/00029-2015.full

Internet

http://openres.ersjournals.com/content/1/2/00029-2015.full

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