Two lamprey Hedgehog genes share non-coding regulatory sequences and expression patterns with gnathostome Hedgehogs.

Hedgehog (Hh) genes play major roles in animal development and studies of their evolution, expression and function point to major differences among chordates. Here we focused on Hh genes in lampreys in order to characterize the evolution of Hh signalling at the emergence of vertebrates. Screening of...

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Bibliographic Details
Main Authors: Shungo Kano, Jin-Hua Xiao, Joana Osório, Marc Ekker, Yavor Hadzhiev, Ferenc Müller, Didier Casane, Ghislaine Magdelenat, Sylvie Rétaux
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-10-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20967201/pdf/?tool=EBI