Single oral dose for HIV pre or post-exposure prophylaxis: user desirability and biological efficacy in macaques

Background: Daily oral pre- or post-exposure prophylaxis (PrEP or PEP) is highly effective in preventing HIV infection. However, many people find it challenging to adhere to a daily oral regimen. Chemoprophylaxis with single oral doses of antiretroviral drugs taken before or after sex may better ada...

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Bibliographic Details
Main Authors:	Ivana Massud, Susan Ruone, Maria Zlotorzynska, Richard Haaland, Patrick Mills, Mian-er Cong, Kristen Kelley, Ryan Johnson, Angela Holder, Chuong Dinh, George Khalil, Yi Pan, Colleen F. Kelley, Travis Sanchez, Walid Heneine, J. Gerardo García-Lerma
Format:	Article
Language:	English
Published:	Elsevier 2020-08-01
Series:	EBioMedicine
Subjects:	HIV pre-exposure prophylaxis HIV post-exposure prophylaxis Macaque models Integrase inhibitors
Online Access:	http://www.sciencedirect.com/science/article/pii/S2352396420302693

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http://www.sciencedirect.com/science/article/pii/S2352396420302693

Single oral dose for HIV pre or post-exposure prophylaxis: user desirability and biological efficacy in macaques

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