3D-printed microplate inserts for long term high-resolution imaging of live brain organoids

3D-printed microplate inserts for long term high-resolution imaging of live brain organoids

Abstract Background Organoids are a reliable model used in the study of human brain development and under pathological conditions. However, current methods for brain organoid culture generate tissues that range from 0.5 to 2 mm of size, which need to be constantly agitated to allow proper oxygenatio...

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Bibliographic Details
Main Authors: Mariana Oksdath Mansilla, Camilo Salazar-Hernandez, Sally L. Perrin, Kaitlin G. Scheer, Gökhan Cildir, John Toubia, Kristyna Sedivakova, Melinda N. Tea, Sakthi Lenin, Elise Ponthier, Erica C. F. Yeo, Vinay Tergaonkar, Santosh Poonnoose, Rebecca J. Ormsby, Stuart M. Pitson, Michael P. Brown, Lisa M. Ebert, Guillermo A. Gomez
Format: Article
Language:English
Published: BMC 2021-04-01
Series:BMC Biomedical Engineering
Subjects:
Brain organoids
Live-imaging
Fluorescence microscopy
Glioblastoma
Online Access:https://doi.org/10.1186/s42490-021-00049-5

Internet

https://doi.org/10.1186/s42490-021-00049-5

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